Boneo Canine® Maintenance - Bio-Rep Animal Health

Boneo Canine® Maintenance Formula is an all-natural dog supplement that helps build strong bones and support healthy joint function. Unlike traditional supplements (glucosamine, chondroitin and MSM) that only target the joints, our patented lactoferrin-based supplement is the first to address a dog's ENTIRE skeletal system – including the joints AND bones.


Number of Bottles


Why Boneo Canine®?

Boneo Canine® is packed with natural premium ingredients and our patented Neo-PORTIN® Complex to support all of your dog's bones – including the joints – and keep your pup moving at their best.

  • Promotes healthy bone remodeling
  • Maintains healthy cartilage
  • Supports joint comfort
  • Improves joint mobility and function

The Science Behind Boneo Canine®

Boneo Canine® Maintenance Formula is made with premium, all-natural ingredients that have been independently tested for purity. Each chewable liver and sausage flavored tablet contains over 325 mg of active ingredients combined to create the ultimate bone and joint support for your furry friend.

+ RNase-enriched Lactoferrin (R-ELF)
+ Coenzyme Q10
+ β-Glucan

Neo-PORTIN® Complex is an exclusive blend of Ribonuclease-enriched Lactoferrin (R-ELF), Coenzyme-Q10 and β-Glucan. R-ELF is a lactose-free milk-derived protein that has been well-documented for role in supporting canine skeletal health.

+ Vitamin C
+ Vitamin B6
+ Vitamin K
+ Vitamin D3
+ Vitamin E

Bone Co-Factors are included in the formula to facilitate different chemical reactions that benefit your dog's skeletal health. Vitamins serve as nutrient activators and assist in absorption. For example, Vitamin D3 is an important bone health nutrient because it is required to absorb calcium into the bones.

+ Calcium
+ Magnesium
+ Manganese
+ Zinc
+ Boron

Bone Minerals, such as calcium and magnesium, make up the building blocks that are essential for strong bones and joints. The bone's mineral content, particularly calcium, helps define the skeleton's rigidity and ability to provide structural support to the body.

+ Quercetin
+ Selenium

Antioxidants function as coolants to help minimize damage caused by free radicals ("heat") generated during normal physical activity and aging. Free radicals are unstable molecules that can cause wear and tear (or "oxidative stress") to your dog's skeletal system. Quercetin and selenium, for example, are well documented for their antioxidant properties.

Directions For Use

Boneo Canine® is great for dogs of all ages, sizes, and breeds! Give Boneo Canine® to your dog daily for the best bone maintenance results.

Feed tablet(s) to your dog whole or crush into pieces/powder and mix with your dog's food 1-3 times per day. Yummy liver and sausage flavor in every bite!




Under 10 LBS

1 Tablet


11 - 50 LBS

2 Tablets


Over 50 LBS

3 Tablets



Frequently Asked Questions

(and their answers)

How long will it take to see results?

While individual results vary, you should see positive results from Boneo Canine® within 4 weeks. Also, if for any reason you are not satisfied with your purchase, this product is backed by the Bio-Rep Satisfaction Guarantee!

Does Boneo Canine® contain glucosamine?

No, Boneo Canine® does not contain glucosamine, chondroitin or MSM. As a result, you can use it as a glucosamine-alternative (if you dog has sensitivities to glucosamine or does not respond well to it). It can also safely be used in conjunction with a glucosamine, chondroitin or MSM supplement.

How do I know if this product is right for my dog?

Boneo Canine® is safe and effective for dogs of all ages, sizes and breeds. This product is great for puppies who could use some extra support during their awkward growing phases (particularly large breeds), small or teacup-size dogs who can benefit from strengthening their fragile bones and joints, agility or working dogs who experience aches and pains from over-exertion, and senior dogs who need extra bone and joint support to support a good quality of life. It is also a great option to help support dogs after an orthopedic procedure or broken-bone/fracture (under the recommendation and supervision of a licensed veterinarian). For questions about your dog's specific needs, however, you should always consult your veterinarian. Your veterinarian has the best understanding of your dog’s health, nutrition, and supplement needs.

What's lactoferrin, and is it safe for my dog?

Lactoferrin is an all-natural glycoprotein that is found in breast milk, tears and other body fluids of mammals. Best known as an iron-binding protein, lactoferrin is a multi-functional protein that has been extensively studied for its immune-friendly properties, as well as its role in regulating the gastrointestinal system and promoting skeletal health. Lactoferrin is currently used as a food additive in a number of products including infant formula, human bone health supplements, digestive health supplements, and products intended for sports nutrition.

Milk-Derived Lactoferrin has been recognized as GRAS (Generally Recognized as Safe) by the U.S. Food and Drug Administration [21 CFR.170.36(f)]. It is an all-natural protein that already exists in the bodies of most mammals, including dogs. At Bio-Rep, we’ve taken further steps to ensure your dog’s health and safety. We source our lactoferrin only from disease-free cow’s milk in Europe and US and ensure that it has undergone a strict purification process. Furthermore, you can rest assured that our lactoferrin is completely lactose-free and safe for dogs with dairy sensitivities.

Can I give Boneo Canine® to my other animals?

The Boneo Canine® line has been designed specially for dogs (particularly with dosages of nutrients) and is recommended for use in dogs only.

How long does shipping take?

You should receive your bottles of Boneo Canine® within 2-3 business days of your order date (excluding holidays and weekends).

Can I cancel my subscription at anytime?

Absolutely! You can cancel your subscription within your user account section or by contacting us directly. The cancellation will be effective immediately and you will not be billed for any future subscription orders.

Customer Reviews

Based on 46 reviews
Misty F
We love Boneo!

Our fur baby was 6 months old when he lost one of his front arms. We researched and researched trying to find a bone AND joint supplement to help his other bones grow and remain healthy. He has been taking Boneo for over a year and he sits and waits patiently every night at 8:30pm for his Boneo. He is now a little over two years old and he's strong and as fast as ever. Thank you Boneo!

Thanks for sharing your heartfelt story about your pup and how Boneo helped him! Receiving such positive feedback inspires us to do what we do. Wising the best for your adorable pup :)

Really good

My puppy had a four (!!) fractures on his toes and the vet was surprised how well it healed - I have him this supplement during his 6 weeks recovery and I think it helped.

Thank you for sharing your experience! Hope your puppy is doing well :)

Carolina P.
Good product

My dog's spams have improved

We're so happy to hear that, Carolina!

Rosa Palmer
Is a great product and the dogs love the flavor so is easy for given to them

My pet loved this supplement

Charlene Wyckoff
Try this Before surgery on your 4 legged family member 🥰

Our Yorkie Axel tore his ACL. We were told about BONEO! This is truly a Amazing supplement! Within a week, it has helped him ! I am not a Veterinarian, and our Yorkie is not going to be a race dog, BUT, he is able not to ‘TOE TIP’ and use his foot. He was scheduled for surgery before we started this supplement , and the morning of surgery , the doctor wanted to see how he was walking , and the Doctor said ‘that if this was my dog I wouldn’t do surgery’! I had veteranians research what is in this and it’s all good vitamins and minerals ! I’m not getting paid by BONEO , but before you pay thousands of $$$ for surgery, try this FIRST !